The Best Spa Hotels and Yoga Retreats in Key West, Florida

Soak up the tranquil vibes at Southernmost Beach Resort in Key West
Soak up the tranquil vibes at Southernmost Beach Resort in Key West | Courtesy of Southernmost Beach Resort / Expedia
Vesna Maric

Key West, Florida’s southernmost point, is an island more known for its coral reefs and diving opportunities than its beaches. Closer to Cuba than to Miami, distance-wise, it was referred to as Cayo Hueso in Spanish, and changed hands several times between colonial powers before it became part of the US. Take advantage of the plethora of water sports on offer, as well as the active nightlife, before relaxing in one of the best spa hotels in Key West, bookable with Culture Trip.

Ocean Key Resort and Spa, for Thai and Balinese treatments

Resort, Spa Hotel

Atmospheric outdoor bar area lit up at night next to long jacuzzi at Ocean Key Resort and Spa in Key West
Courtesy of Ocean Key Resort and Spa / Expedia

Choose from views of the Gulf of Mexico or Duval Street at this sumptuous hotel, positioned right on Duval and adjacent to Mallory Square in historic Old Town Key West. Tons of natural light from the many windows flood the aquamarine-walled rooms with colorful bedding and contemporary art pieces. Each room has its own balcony and large marble bath with whirlpool tub. The luxurious spa offers Balinese and Thai treatments that are sure to leave your skin super soft.

Pier House, for signature milk and honey treatments

Resort

Pier House jutting out over the water with private beach area in Key West, Florida
Courtesy of Pier House / Expedia

Pier House has one of the best spas in Key West, as well as a private white-sand beach and rooms overlooking either the Gulf of Mexico or tropical greenery. The cream-colored rooms and suites are modern and comfortable, with custom-designed pillows and nature-themed artwork in the higher-end accommodations. The hotel has Key West’s only full-service spa, with such marvels as a signature honey and coconut milk treatment that includes exfoliation, wrap and a scalp massage.

Hyatt Centric Key West Resort & Spa, for a plethora of massages

Resort

Spa space with center settee and doors to different treatment rooms at Hyatt Centric Key West Resort and Spa
Courtesy of Hyatt Centric Key West Resort and Spa / Expedia

The Hyatt Centric offers bright rooms with large windows and private balconies overlooking the teal waves. The simple, clean, white decor is broken up with splashes of color. Have drinks at the Blue Mojito Bar and Grill, followed by dinner at the on-site SHOR American Seafood Grill restaurant serving local seafood and seasonal offerings, which you can enjoy on a deck overlooking the water. The Jala Spa is perfect for treating yourself to some pampering after a hard day at the beach.

Oceans Edge Resort & Marina, for tranquil island life

Resort

Oceans Edge Resort pool area with plush lounge chairs, blue umbrellas and row of palm trees in Key West, Florida
Courtesy of Oceans Edge Resort and Marina / Expedia

The six swimming pools and 165-slip full-service marina at the end of a slender finger of land that’s part of Stock Island make Oceans Edge the place for those who want to get away from it all – though there’s an hourly shuttle to downtown Key West for those who want to explore the town. The rooms are breezy and decorated in nautical white and navy, and you can enjoy the slower pace of life by pedaling around the island on a complimentary bicycle. Spa activities include poolside yoga and paddleboarding fitness classes.

Southernmost Beach Resort, for sessions with a personal trainer

Resort

Shaded outdoor spa treatment area with massage table overlooking the water at Southernmost Beach Resort in Key West
Courtesy of Southernmost Beach Resort / Expedia

Sitting in the historic Old Town on Key West’s Atlantic Coast, Southernmost manages to be in the midst of all the action while maintaining tranquil vibes. The rooms and suites are sophisticated and tasteful, and the balconies overlook the lovely tropical gardens. The Petite Spa has a daily choice of fitness classes as well as a plethora of treatments; there is a team of yoga instructors, personal trainers, massage therapists and beauticians, all there to serve the needs of your body. The on-site restaurant serves a fusion of Caribbean and Asian dishes.

Gardens Hotel, for couples’ massages and signature drinks

Boutique Hotel, Bed and Breakfast

Outdoor pool area surrounded by lush foliage at the Gardens Hotel, Key West
Courtesy of the Gardens Hotel / Expedia

Eccentric, cool rooms and cottages are the order of the day at this romantic luxury boutique hotel, with four-poster beds, quirky art and assorted creature comforts. LGBTQ-friendly, and with a focus on romance, Gardens Hotel is popular with those who want to spend a weekend or a week with their significant other. Order a chilled bucket of champagne to your room, or partake in a couple’s massage while sipping the hotel’s signature cocktail, the Gardenia. The hotel also has a jazz season, with performances in the gardens.

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Culture Trip launched in 2011 with a simple yet passionate mission: to inspire people to go beyond their boundaries and experience what makes a place, its people and its culture special and meaningful — and this is still in our DNA today. We are proud that, for more than a decade, millions like you have trusted our award-winning recommendations by people who deeply understand what makes certain places and communities so special.

Increasingly we believe the world needs more meaningful, real-life connections between curious travellers keen to explore the world in a more responsible way. That is why we have intensively curated a collection of premium small-group trips as an invitation to meet and connect with new, like-minded people for once-in-a-lifetime experiences in three categories: Culture Trips, Rail Trips and Private Trips. Our Trips are suitable for both solo travelers, couples and friends who want to explore the world together.

Culture Trips are deeply immersive 5 to 16 days itineraries, that combine authentic local experiences, exciting activities and 4-5* accommodation to look forward to at the end of each day. Our Rail Trips are our most planet-friendly itineraries that invite you to take the scenic route, relax whilst getting under the skin of a destination. Our Private Trips are fully tailored itineraries, curated by our Travel Experts specifically for you, your friends or your family.

We know that many of you worry about the environmental impact of travel and are looking for ways of expanding horizons in ways that do minimal harm - and may even bring benefits. We are committed to go as far as possible in curating our trips with care for the planet. That is why all of our trips are flightless in destination, fully carbon offset - and we have ambitious plans to be net zero in the very near future.

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